If you use steroids derived from the hormone DHT (Masteron and Proviron, for example), then levels can increase to the point of side effects developing. When it comes to steroid use, HCG is used in post-cycle therapy to perform the same task due to the reduction in normal testosterone production activity. Arimistane is another aromatase inhibitor that stops testosterone from converting to estrogen, thus preventing the estrogenic side effects of anabolic steroid use. Commonly used aromatizing steroids like Testosterone and Dianabol can quickly raise your estrogen levels to bring on side effects like gynecomastia and water retention. Post-cycle therapy may not be considered essential, as natural testosterone levels typically recover in most steroid users. So once again, when using a 19-Nor steroid, you should prioritize the control of prolactin, and you can then make this side effect one that can be avoided. But you don’t have to suffer with either gyno or prolactin! Vitamin B6 is also helpful and recommended to be included in your cycle. The main category of drugs that are effective here is called dopamine agonists. See the medications above for suggestions on reducing overall DHT levels by taking Finasteride at a low dose and/or applying a topical RU to target acne directly. This should work quickly and have those gyno symptoms reduced and reversed within just a few days. If, for whatever reason, you’re starting to notice gyno symptoms developing (swelling and/or tenderness), you’ll want to get on to it quickly. Arimidex or Aromasin are the two go-to AIs for gyno prevention. In other words, there’s no single dose I can give you that "works" to prevent gyno. It’s not just what you use but how you dose it with your steroid dosage. Gyno is more likely to be a problem for new steroid users AND those who don’t bother to learn the basics of preventing it. With what we now know about gyno and how/why it develops, there’s no reason you shouldn’t be able to stop it from happening. Many users will take Aromasin both during and right after a steroid cycle to keep estrogen levels down. Like Aromasin, Arimidex is often taken during a steroid cycle as well as for post-cycle therapy to prevent a rise of estrogen from occurring at any part of the cycle. When you use Arimidex on a cycle, you can take it every 2-3 days because of its longer half-life, and it’s very effective at preventing testosterone conversion to estrogen. Aromatase inhibitors (AI) were developed as a breast cancer treatment for women, and they’re still used for that purpose today. However, some bodybuilders tend to take it during the cycle as well as right after it to keep testosterone levels high by preventing the binding of estrogen. Most steroid users prefer to use AIs on cycles to mitigate estrogenic side effects, with selective estrogen receptor modulators (SERMs) being more of a PCT choice. It also serves as an impressive stimulator of endogenous Testosterone production, ideal for proper hormonal recovery following the end of an anabolic steroid cycle. Nolvadex would likely be beneficial in anabolic steroid using athletes and bodybuilders that do not wish for a decrease in Estrogen levels, but instead wish to block Estrogen’s effects in select tissues. The use of Nolvadex during a cycle will not counter-act the Testosterone suppression of anabolic steroid use and will not keep endogenous Testosterone production going amidst the use of suppressive compounds. In this case, Nolvadex is usually administered during PCT, which is immediately after the anabolic steroid cycle is complete and all anabolic steroids are clear from the individual’s system. Medically, Nolvadex (Tamoxifen) is utilized as a medication in the treatment of 6 different types of female breast cancer. You might be lucky to have zero tendency to develop acne, no matter what steroids you use. And if you’re using any steroids that are DHT derivatives? When you reduce your circulating levels of DHT too far, you’ll experience adverse effects (low libido, fatigue, depression, poor muscle mass). Hair loss is, unfortunately, a well-known and often expected side effect when using certain steroids. The other is a category of drugs called non-steroidal anti-androgens (NSAA).